St. Louis Cam from EarthCam
I'm not sure why I haven't seen this before, but there's apparently an EarthCam permanently pointed at Downtown St. Louis from across the river in the Malcolm W. Martin Memorial Park, and it gives a live view of the iconic St. Louis cityscape 24x7. On a nice crisp fall evening like tonight, it looks very nice:
You can watch downtown St. Louis live on the EarthCam - St. Louis website.